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MSH5 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MSH5 Antibody (Center) AP16931c
    MSH5 Antibody (Center) (Cat. #AP16931c) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the MSH5 antibody detected the MSH5 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O43196
Other Accession NP_079535.4, NP_002432.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 92875 Da
Antigen Region 525-552 aa
Additional Information
Gene ID 4439
Other Names MutS protein homolog 5, hMSH5, MSH5
Target/Specificity This MSH5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 525-552 amino acids from the Central region of human MSH5.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMSH5 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MSH5
Function Involved in meiotic recombination. Facilitate crossovers between homologs during meiosis (By similarity).
Tissue Location Ubiquitous, but highly expressed in testis, and thymus
Citations (0)

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This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms heterooligomers with another member of this family, mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases, including IgA deficiency, common variable immunodeficiency, and premature ovarian failure. Alternative splicing results multiple transcript variants.


Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010)
Pozo, N.D., et al. Hum. Immunol. 71(9):861-864(2010)
Snowden, T., et al. J. Biol. Chem. 283(1):145-154(2008)
Sekine, H., et al. Proc. Natl. Acad. Sci. U.S.A. 104(17):7193-7198(2007)
Yi, W., et al. Biochem. Biophys. Res. Commun. 332(2):524-532(2005)

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$ 295.00
$ 99.00
Cat# AP16931c
(40 western blots)
Availability: In Stock
Bulk Size
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