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NCDN Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - NCDN Antibody (N-term) AP16948a
    NCDN Antibody (N-term) (Cat. #AP16948a) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the NCDN antibody detected the NCDN protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UBB6
Other Accession Q9Z0E0, Q2KJ97, NP_001014841.1, NP_055099.1
Reactivity Human
Predicted Bovine, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 78864 Da
Antigen Region 114-144 aa
Additional Information
Gene ID 23154
Other Names Neurochondrin, NCDN, KIAA0607
Target/Specificity This NCDN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 114-144 amino acids from the N-terminal region of human NCDN.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNCDN Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KIAA0607
Function Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling (By similarity). Required for the spatial learning process. Acts as a negative regulator of Ca(2+)-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin- concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction. May be involved in bone metabolism. May also be involved in neurite outgrowth.
Cellular Location Cytoplasm, cytosol. Cell projection, dendrite. Note=Localizes to somatic regions of neurons
Tissue Location Abundantly expressed in whole adult brain and in all individual brain regions examined, including spinal cord Weakly expressed in ovary, testis, fetal brain and small intestine.
Research Areas
Citations (0)

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This gene encodes a leucine-rich cytoplasmic protein, which is highly similar to a mouse protein that negatively regulates Ca/calmodulin-dependent protein kinase II phosphorylation and may be essential for spatial learning processes. Several alternatively spliced transcript variants of this gene have been described.


Dateki, M., et al. J. Biol. Chem. 280(21):20503-20508(2005)
Mochizuki, R., et al. Biochem. Biophys. Res. Commun. 310(4):1219-1226(2003)
Tchernev, V.T., et al. Mol. Med. 8(1):56-64(2002)
Ohoka, Y., et al. Biochem. Biophys. Res. Commun. 280(1):237-243(2001)
Mochizuki, R., et al. Biochim. Biophys. Acta 1490(3):367-368(2000)

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$ 295.00
$ 99.00
Cat# AP16948a
(40 western blots)
Availability: In Stock
Bulk Size
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