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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   SRM Antibody (Center)   

SRM Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SRM Antibody (Center) AP16953c
    SRM Antibody (Center) (Cat. #AP16953c) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SRM antibody detected the SRM protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P19623
Other Accession Q64674, NP_003123.2
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 33825 Da
Antigen Region 158-187 aa
Additional Information
Gene ID 6723
Other Names Spermidine synthase, SPDSY, Putrescine aminopropyltransferase, SRM, SPS1, SRML1
Target/Specificity This SRM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 158-187 amino acids from the Central region of human SRM.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSRM Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SRM
Synonyms SPS1, SRML1
Function Catalyzes the production of spermidine from putrescine and decarboxylated S-adenosylmethionine (dcSAM). Has a strong preference for putrescine as substrate, and has very low activity towards 1,3-diaminopropane. Has extremely low activity towards spermidine.
Research Areas
Citations (0)

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The polyamines putrescine, spermine, and spermidine are ubiquitous polycationic mediators of cell growth and differentiation. Spermidine synthase is one of four enzymes in the polyamine-biosynthetic pathway and carries out the final step of spermidine biosynthesis. This enzyme catalyzes the conversion of putrescine to spermidine using decarboxylated S-adenosylmethionine as the cofactor.


Wu, H., et al. Biochemistry 46(28):8331-8339(2007)
Nishikawa, Y., et al. Biochem. J. 321 (PT 2), 537-543 (1997) :
Lakanen, J.R., et al. J. Med. Chem. 38(14):2714-2727(1995)
Kauppinen, L. FEBS Lett. 365(1):61-65(1995)
Kauppinen, L., et al. Biochem. J. 293 (PT 2), 513-516 (1993) :

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$ 295.00
$ 99.00
Cat# AP16953c
(40 western blots)
Availability: In Stock
Bulk Size
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