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GUCY2F Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GUCY2F Antibody (C-term) AP16965B
    GUCY2F Antibody (C-term) (Cat. #AP16965b) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the GUCY2F antibody detected the GUCY2F protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P51841
Other Accession P51842, Q5SDA5, O02740, NP_001513.2
Reactivity Human
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 124850 Da
Antigen Region 828-856 aa
Additional Information
Gene ID 2986
Other Names Retinal guanylyl cyclase 2, RETGC-2, Guanylate cyclase 2F, retinal, Guanylate cyclase F, GC-F, Rod outer segment membrane guanylate cyclase 2, ROS-GC2, GUCY2F, GUC2F, RETGC2
Target/Specificity This GUCY2F antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 828-856 amino acids from the C-terminal region of human GUCY2F.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGUCY2F Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms GUC2F, RETGC2
Function Probably plays a specific functional role in the rods and/or cones of photoreceptors. It may be the enzyme involved in the resynthesis of cGMP required for recovery of the dark state after phototransduction.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Retina. Localized exclusively in the outer nuclear layer and inner segments of the rod and cone photoreceptor cells
Research Areas
Citations (0)

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The protein encoded by this gene is a guanylyl cyclase found predominantly in photoreceptors in the retina. The encoded protein is thought to be involved in resynthesis of cGMP after light activation of the visual signal transduction cascade, allowing a return to the dark state. This protein is a single-pass type I membrane protein. Defects in this gene may be a cause of X-linked retinitis pigmentosa.


Blackford, A., et al. Cancer Res. 69(8):3681-3688(2009)
Helten, A., et al. J. Neurochem. 103(4):1439-1446(2007)
Wood, L.D., et al. Hum. Mutat. 27(10):1060-1061(2006)
Ross, M.T., et al. Nature 434(7031):325-337(2005)
Laura, R.P., et al. Biochemistry 37(32):11264-11271(1998)

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$ 295.00
$ 99.00
Cat# AP16965B
(40 western blots)
Availability: In Stock
Bulk Size
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