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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   KRT6A Antibody (N-term)   

KRT6A Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - KRT6A Antibody (N-term) AP16974a
    KRT6A Antibody (N-term) (Cat. #AP16974a) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the KRT6A antibody detected the KRT6A protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P02538
Other Accession O95678, NP_005545.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 60045 Da
Antigen Region 135-164 aa
Additional Information
Gene ID 3853
Other Names Keratin, type II cytoskeletal 6A, Cytokeratin-6A, CK-6A, Cytokeratin-6D, CK-6D, Keratin-6A, K6A, Type-II keratin Kb6, Hom s 5, KRT6A, K6A, KRT6D
Target/Specificity This KRT6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-164 amino acids from the N-terminal region of human KRT6A.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKRT6A Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KRT6A
Synonyms K6A, KRT6D
Function Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair.
Tissue Location Constitutively expressed in distinct types of epithelia such as those in oral mucosa, esophagus, papillae of tongue and hair follicle outer root sheath
Research Areas
Citations (0)

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The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq].


Dereure, O. Ann Dermatol Venereol 137(5):423-424(2010)
Trost, A., et al. Mech. Ageing Dev. 131(5):346-353(2010)
Yang, L., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 27(1):66-68(2010)
Millar, E.K., et al. J. Clin. Oncol. 27(28):4701-4708(2009)
Bai, Z.L., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 26(5):514-517(2009)

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$ 295.00
$ 99.00
Cat# AP16974a
(40 western blots)
Availability: In Stock
Bulk Size
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