|Application ||WB, E|
|Other Accession||NP_004240.2, NP_001017979.1|
|Calculated MW||24841 Da|
|Antigen Region||119-147 aa|
|Other Names||Ras-related protein Rab-28, RAB28|
|Target/Specificity||This RAB28 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 119-147 amino acids from the Central region of human RAB28.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RAB28 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton, cilium basal body. Note=Expressed in the basal body and ciliary rootlet of the photoreceptors.|
|Tissue Location||Isoform S is detected in most tissues investigated: cortex, liver, kidney, skeletal muscle, adipose tissue, testis, urothelium, lung, bone marrow and retinal pigment epithelium (RPE). Isoform L 2 is widely and abundantly expressed all tissues. Isoform 3 is highly expressed in heart, lung, bone marrow, retina, brain, and RPE.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the Rab subfamily of Ras-related small GTPases. The encoded protein may be involved in regulating intracellular trafficking. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 9 and X.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Lee, S.H., et al. FEBS Lett. 582(29):4107-4111(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Stenmark, H., et al. Genome Biol. 2 (5), REVIEWS3007 (2001) :
Pereira-Leal, J.B., et al. J. Mol. Biol. 301(4):1077-1087(2000)
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