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SEPP1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SEPP1 Antibody (Center) AP16986c
    SEPP1 Antibody (Center) (Cat. #AP16986c) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the SEPP1 antibody detected the SEPP1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P49908
Other Accession NP_001078955.1, NP_005401.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 43174 Da
Antigen Region 233-262 aa
Additional Information
Gene ID 6414
Other Names Selenoprotein P, SeP, SEPP1, SELP
Target/Specificity This SEPP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 233-262 amino acids from the Central region of human SEPP1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSEPP1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SEPP1
Synonyms SELP
Function Might be responsible for some of the extracellular antioxidant defense properties of selenium or might be involved in the transport of selenium. May supply selenium to tissues such as brain and testis.
Cellular Location Secreted.
Tissue Location Made in the liver and heart and secreted into the plasma. It is also found in the kidney
Citations (0)

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This gene encodes a selenoprotein containing multiple selenocysteine (Sec) residues, which are encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenoprotein genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This selenoprotein is an extracellular glycoprotein, and is unusual in that it contains 10 Sec residues per polypeptide. It is a heparin-binding protein that appears to be associated with endothelial cells, and has been implicated to function as an antioxidant in the extracellular space. Several transcript variants, encoding either the same or different isoform, have been found for this gene.


Sun, W., et al. Br. J. Nutr. 104(9):1283-1287(2010)
Roman, M., et al. Transl Res 156(4):242-250(2010)
Meplan, C., et al. Carcinogenesis 31(6):1074-1079(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Takemoto, A.S., et al. Ethn Dis 20 (1 SUPPL 1), S1-S925 (2010) :

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Cat# AP16986c
(40 western blots)
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