|Application ||WB, E|
|Other Accession||NP_919337.1, NP_001971.2|
|Calculated MW||33341 Da|
|Antigen Region||60-89 aa|
|Other Names||Syntaxin-2, Epimorphin, STX2, EPIM, STX2A, STX2B, STX2C|
|Target/Specificity||This STX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-89 amino acids from the N-terminal region of human STX2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||STX2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||EPIM, STX2A, STX2B, STX2C|
|Function||Essential for epithelial morphogenesis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.|
|Cellular Location||Membrane; Single-pass type IV membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified.
Chen, C.S., et al. J. Biol. Chem. 284(11):6877-6884(2009)
Okugawa, Y., et al. J. Invest. Dermatol. 128(8):1884-1893(2008)
Flaumenhaft, R., et al. Blood 110(5):1492-1501(2007)
Low, S.H., et al. Mol. Biol. Cell 17(2):977-989(2006)
Band, A.M., et al. BMC Cell Biol. 6 (1), 26 (2005) :
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