STX2 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | P32856 |
Other Accession | NP_919337.1, NP_001971.2 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 33341 Da |
Antigen Region | 60-89 aa |
Gene ID | 2054 |
---|---|
Other Names | Syntaxin-2, Epimorphin, STX2, EPIM, STX2A, STX2B, STX2C |
Target/Specificity | This STX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 60-89 amino acids from the N-terminal region of human STX2. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | STX2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | STX2 |
---|---|
Synonyms | EPIM, STX2A, STX2B, STX2C |
Function | Essential for epithelial morphogenesis. May mediate Ca(2+)- regulation of exocytosis acrosomal reaction in sperm. |
Cellular Location | Membrane; Single-pass type IV membrane protein. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified.
References
Chen, C.S., et al. J. Biol. Chem. 284(11):6877-6884(2009)
Okugawa, Y., et al. J. Invest. Dermatol. 128(8):1884-1893(2008)
Flaumenhaft, R., et al. Blood 110(5):1492-1501(2007)
Low, S.H., et al. Mol. Biol. Cell 17(2):977-989(2006)
Band, A.M., et al. BMC Cell Biol. 6 (1), 26 (2005) :
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