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RPN1 Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP16998b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP16998b-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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- Citiations : 0
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RPN1 Antibody (C-term) - Product info | |
| Application | WB
|
| Primary Accession | P04843 |
| Other Accession | P07153, Q9GMB0, Q4R4T0, NP_002941.1 |
| Reactivity | Human |
| Predicted | Pig, Monkey, Rat |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 68569 Da |
RPN1 Antibody (C-term) - Additional info | |
| Gene ID 6184 | |
| Other Names RPN1; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 67 kDa subunit; Ribophorin I; Ribophorin-1 | |
| Target/Specificity This RPN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 558-587 amino acids from the C-terminal region of human RPN1. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions RPN1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
RPN1 Antibody (C-term) - Protein Information | |
| Name RPN1 | |
| Function Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains | |
| Cellular Location Endoplasmic reticulum membrane; Single-pass type I membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV | |
| Tissue Location Expressed in all tissues tested. | |
RPN1 Antibody (C-term) - Related products
AP16998b: RPN1 Antibody (C-term)
AP2409a: Ribophorin (RPN1) Antibody (N-term)
AP2409b: Ribophorin (RPN1) Antibody (C-term)
RPN1 Antibody (C-term) - Application data
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RPN1 Antibody (C-term) (Cat. #AP16998b) western blot analysis in WiDr cell line lysates (35ug/lane).This demonstrates the RPN1 antibody detected the RPN1 protein (arrow).
RPN1 Antibody (C-term) - Research Areas
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BACKGROUND
This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein forms part of the regulatory subunit of the 26S proteasome and may mediate binding of ubiquitin-like domains to this proteasome.
REFERENCES
Ruiz-Canada, C., et al. Cell 136(2):272-283(2009) Wang, L., et al. Cancer Epidemiol. Biomarkers Prev. 17(12):3558-3566(2008) Wilson, C.M., et al. Proc. Natl. Acad. Sci. U.S.A. 105(28):9534-9539(2008) Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) : Chi, A., et al. J. Proteome Res. 5(11):3135-3144(2006)
