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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   IL23R Antibody (C-term)   

IL23R Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - IL23R Antibody (C-term) AP17012b
    IL23R Antibody (C-term) (Cat. #AP17012b) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the IL23R antibody detected the IL23R protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q5VWK5
Other Accession NP_653302.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 71722 Da
Antigen Region 428-457 aa
Additional Information
Gene ID 149233
Other Names Interleukin-23 receptor, IL-23 receptor, IL-23R, IL23R
Target/Specificity This IL23R antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 428-457 amino acids from the C-terminal region of human IL23R.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIL23R Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IL23R
Function Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Expressed by monocytes, Th1, Th0, NK and dendritic cells. Isoform 1 is specifically expressed in NK cells
Research Areas
Citations (0)

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The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.


Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
Chen, J., et al. Mol. Carcinog. 49(10):862-868(2010)
Mizuki, N., et al. Nat. Genet. 42(8):703-706(2010)
Remmers, E.F., et al. Nat. Genet. 42(8):698-702(2010)
Elmaagacli, A.H., et al. Bone Marrow Transplant. (2010) In press :

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Cat# AP17012b
(40 western blots)
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