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RCOR1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - RCOR1 Antibody (N-term) AP17018A
    All lanes : Anti-RCOR1 Antibody (N-term) at 1:2000 dilution Lane 1: HT-29 whole cell lysate Lane 2: Jurkat whole cell lysate Lane 3: LNCaP whole cell lysate Lane 4: MOLT-4 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 53 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - RCOR1 Antibody (N-term) AP17018A
    RCOR1 Antibody (N-term) (Cat. #AP17018a) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the RCOR1 antibody detected the RCOR1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UKL0
Other Accession Q8CFE3, NP_055971.1
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 53028 Da
Antigen Region 101-130 aa
Additional Information
Gene ID 23186
Other Names REST corepressor 1, Protein CoREST, RCOR1, KIAA0071, RCOR
Target/Specificity This RCOR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 101-130 amino acids from the N-terminal region of human RCOR1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRCOR1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RCOR1
Synonyms KIAA0071, RCOR
Function Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval. Plays a central role in demethylation of Lys-4 of histone H3 by promoting demethylase activity of KDM1A on core histones and nucleosomal substrates. It also protects KDM1A from the proteasome. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development and controls hematopoietic differentiation.
Cellular Location Nucleus {ECO:0000255|PROSITE- ProRule:PRU00512, ECO:0000255|PROSITE-ProRule:PRU00624, ECO:0000269|PubMed:10734093, ECO:0000269|PubMed:15897453} Note=Upon infection by HSV-1, it is partially translocated into the cytoplasm in an HSV-1-dependent manner
Tissue Location Ubiquitously expressed.
Citations (0)

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The RCOR gene encodes a functional corepressor required for regulation of neural-specific gene expression.[supplied by OMIM].


Xiao, J., et al. J. Orthop. Res. 28(12):1569-1575(2010)
Everett, R.D. J. Virol. 84(7):3695-3698(2010)
Das, C., et al. J. Mol. Biol. 397(1):1-12(2010)
Laurent, B., et al. Stem Cells 27(9):2153-2162(2009)
Wang, Y., et al. Cell 138(4):660-672(2009)

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$ 295.00
$ 99.00
Cat# AP17018A
(40 western blots)
Availability: In Stock
Bulk Size
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