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HRH4 Antibody (C-term)
Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q96LD9 |
| Other Accession | Q9H3N8 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 44470 Da |
| Antigen Region | 359-390 aa |
| Other Names | Histamine receptor H4; |
|---|---|
| Target/Specificity | This HRH4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 359-390 amino acids from the C-terminal region of human HRH4. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | HRH4 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | H4 {ECO:0000313|EMBL:AAL09297.1} |
|---|---|
| Cellular Location | Cell membrane {ECO:0000256|ARBA:ARBA00004651}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004141} |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H4 belongs to the family 1 of G protein-coupled receptors and has the highest homology to histamine receptor H3 among known G protein-coupled receptors.
References
Lippert, U., et al., J. Invest. Dermatol. 123(1):116-123 (2004).
Coge, F., et al., Biochem. Biophys. Res. Commun. 284(2):301-309 (2001).
Morse, K.L., et al., J. Pharmacol. Exp. Ther. 296(3):1058-1066 (2001).
Zhu, Y., et al., Mol. Pharmacol. 59(3):434-441 (2001).
Liu, C., et al., Mol. Pharmacol. 59(3):420-426 (2001).
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