|Application ||WB, E|
|Calculated MW||59608 Da|
|Antigen Region||335-363 aa|
|Other Names||Dual specificity tyrosine-phosphorylation-regulated kinase 4, DYRK4|
|Target/Specificity||This DYRK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 335-363 amino acids from the Central region of human DYRK4.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DYRK4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Possible non-essential role in spermiogenesis.|
|Cellular Location||Isoform 1: Cytoplasm|
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Provided below are standard protocols that you may find useful for product applications.
Dual-specificity kinases, such as DYRK4, play key roles in cell proliferation, survival, and development (Zhang et al., 2005 [PubMed 15607427]).
Sacher, F., et al. Mol. Cell. Endocrinol. 267 (1-2), 80-88 (2007) :
Zhang, D., et al. Genomics 85(1):117-130(2005)
Nat. Genet. 26(3):345-348(2000)
Becker, W., et al. J. Biol. Chem. 273(40):25893-25902(1998)
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