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SNRNP70 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SNRNP70 Antibody (Center) AP17045c
    SNRNP70 Antibody (Center) (Cat. #AP17045c) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the SNRNP70 antibody detected the SNRNP70 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P08621
Other Accession Q62376, Q1RMR2, NP_003080.2
Reactivity Human
Predicted Bovine, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 51557 Da
Antigen Region 195-223 aa
Additional Information
Gene ID 6625
Other Names U1 small nuclear ribonucleoprotein 70 kDa, U1 snRNP 70 kDa, U1-70K, snRNP70, SNRNP70, RNPU1Z, RPU1, SNRP70, U1AP1
Target/Specificity This SNRNP70 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 195-223 amino acids from the Central region of human SNRNP70.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSNRNP70 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SNRNP70
Synonyms RNPU1Z, RPU1, SNRP70, U1AP1
Function Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRNP70 binds to the loop I region of U1-snRNA. The truncated isoforms cannot bind U1-snRNA.
Cellular Location Nucleus. Nucleus speckle. Nucleus, nucleoplasm. Note=Colocalizes with SCNM1 and LUC7L2 in nuclear speckles.
Research Areas
Citations (0)

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SNRNP70 mediates the splicing of pre-mRNA by binding to the loop I region of U1-snRNA. The truncated isoforms cannot bind U1-snRNA.


Spiluttini, B., et al. J. Cell. Sci. 123 (PT 12), 2085-2093 (2010) :
Tzang, B.S., et al. J. Biomed. Sci. 17, 40 (2010) :
Parente Costa, L., et al. J. Autoimmun. 33(2):121-124(2009)
Hernandez, H., et al. PLoS ONE 4 (9), E7202 (2009) :
Palafox Sanchez, C.A., et al. Arthritis Res. Ther. 11 (1), R27 (2009) :

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$ 295.00
$ 99.00
Cat# AP17045c
(40 western blots)
Availability: In Stock
Bulk Size
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