|Application ||WB, E|
|Calculated MW||63066 Da|
|Antigen Region||501-529 aa|
|Other Names||Fatty-acid amide hydrolase 1, Anandamide amidohydrolase 1, Oleamide hydrolase 1, FAAH, FAAH1|
|Target/Specificity||This FAAH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 501-529 amino acids from the C-terminal region of human FAAH.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||FAAH Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes polyunsaturated substrate anandamide preferentially as compared to monounsaturated substrates.|
|Cellular Location||Endomembrane system; Single-pass membrane protein. Cytoplasm, cytoskeleton. Note=Seems to be attached to intracellular membranes and a portion of the cytoskeletal network|
|Tissue Location||Highly expressed in the brain, small intestine, pancreas, skeletal muscle and testis. Also expressed in the kidney, liver, lung, placenta and prostate|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein that is responsible for the hydrolysis of a number of primary and secondary fatty acid amides, including the neuromodulatory compounds anandamide and oleamide.
Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)
de Luis, D.A., et al. Metab. Clin. Exp. (2010) In press :
Monteleone, P., et al. J Clin Psychopharmacol 30(4):441-445(2010)
Taylor, A.H., et al. Histochem. Cell Biol. 133(5):557-565(2010)
Thors, L., et al. PLoS ONE 5 (8), E12275 (2010) :
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