SUPT7L Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | O94864 |
Other Accession | NP_055675.1 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 46193 Da |
Antigen Region | 186-214 aa |
Gene ID | 9913 |
---|---|
Other Names | STAGA complex 65 subunit gamma, Adenocarcinoma antigen ART1, SPTF-associated factor 65 gamma, STAF65gamma, Suppressor of Ty 7-like, SUPT7L, KIAA0764 |
Target/Specificity | This SUPT7L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-214 amino acids from the Central region of human SUPT7L. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SUPT7L Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SUPT7L |
---|---|
Synonyms | KIAA0764 |
Cellular Location | Nucleus. |
Tissue Location | Expressed at high levels in adenocarcinomas and gliomas and low in esophageal cancers and malignant hematological disease. Also expressed at high level in the thymus, low in peripheral blood mononuclear cells, and lowest in the stomach, small intestine, and skeletal muscle |
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Provided below are standard protocols that you may find useful for product applications.
Background
SUPT7L is a protein subunit of the human STAGA complex (SPT3; (MIM 602947)/TAF9 (MIM 600822)/GCN5 (MIM 602301) acetyltransferase complex), which is a chromatin-modifying multiprotein complex (Martinez et al., 2001 [PubMed 11564863]).
References
Gamper, A.M., et al. Mol. Cell. Biol. 28(8):2517-2527(2008)
Soutoglou, E., et al. Mol. Cell. Biol. 25(10):4092-4104(2005)
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Wang, H.Y., et al. J. Immunol. 174(5):2661-2670(2005)
Gocke, C.B., et al. J. Biol. Chem. 280(6):5004-5012(2005)
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