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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   IQCB1 Antibody (Center)   

IQCB1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - IQCB1 Antibody (Center) AP17066C
    IQCB1 Antibody (Center) (Cat. #AP17066c) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the IQCB1 antibody detected the IQCB1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15051
Other Accession NP_001018865.2, NP_001018864.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 68929 Da
Antigen Region 384-411 aa
Additional Information
Gene ID 9657
Other Names IQ calmodulin-binding motif-containing protein 1, Nephrocystin-5, p53 and DNA damage-regulated IQ motif protein, PIQ, IQCB1, KIAA0036, NPHP5
Target/Specificity This IQCB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 384-411 amino acids from the Central region of human IQCB1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsIQCB1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name IQCB1
Synonyms KIAA0036, NPHP5
Function Involved in ciliogenesis.
Cellular Location Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Note=Localization to the centrosome depends on the interaction with CEP290
Tissue Location Ubiquitously expressed in fetal and adult tissues. Localized to the outer segments and connecting cilia of photoreceptor cells. Up-regulated in a number of primary colorectal and gastric tumors.
Research Areas
Citations (0)

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This gene encodes a nephrocystin protein that interacts with calmodulin and the retinitis pigmentosa GTPase regulator protein. The encoded protein has a central coiled-coil region and two calmodulin-binding IQ domains. It is localized to the primary cilia of renal epithelial cells and connecting cilia of photoreceptor cells. The protein is thought to play a role in ciliary function. Defects in this gene result in Senior-Loken syndrome type 5. Alternative splicing results in multiple transcript variants.


Hildebrandt, F., et al. J. Am. Soc. Nephrol. 20(1):23-35(2009)
Schafer, T., et al. Hum. Mol. Genet. 17(23):3655-3662(2008)
Luo, X., et al. Cancer Res. 65(23):10725-10733(2005)
le Maire, A., et al. Proteins 59(2):347-355(2005)
Mollet, G., et al. Hum. Mol. Genet. 14(5):645-656(2005)

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$ 295.00
$ 99.00
Cat# AP17066C
(40 western blots)
Availability: In Stock
Bulk Size
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