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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   FBXO31 Antibody (Center)   

FBXO31 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - FBXO31 Antibody (Center) AP17068C
    FBXO31 Antibody (Center) (Cat. #AP17068c) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the FBXO31 antibody detected the FBXO31 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q5XUX0
Other Accession B2RYN2, Q3TQF0, NP_079011.3
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 60664 Da
Antigen Region 310-338 aa
Additional Information
Gene ID 79791
Other Names F-box only protein 31, FBXO31, FBX14, FBX31
Target/Specificity This FBXO31 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 310-338 amino acids from the Central region of human FBXO31.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFBXO31 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FBXO31
Synonyms FBX14, FBX31
Function Component of some SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. Specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. May act as a tumor suppressor.
Tissue Location Highly expressed in brain. Expressed at moderate levels in most tissues, except bone marrow
Research Areas
Citations (0)

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Members of the F-box protein family, such as FBXO31, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM].


Rivadeneira, F., et al. Nat. Genet. 41(11):1199-1206(2009)
Santra, M.K., et al. Nature 459(7247):722-725(2009)
Kumar, R., et al. Cancer Res. 65(24):11304-11313(2005)
Jin, J., et al. Genes Dev. 18(21):2573-2580(2004)
Powell, J.A., et al. Genomics 80(3):303-310(2002)

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$ 295.00
$ 99.00
Cat# AP17068C
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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