|Application ||WB, E|
|Other Accession||B4F7A7, Q8CEE0, NP_055494.2|
|Calculated MW||57089 Da|
|Antigen Region||89-117 aa|
|Other Names||Centrosomal protein of 57 kDa, Cep57, FGF2-interacting protein, Testis-specific protein 57, Translokin, CEP57, KIAA0092, TSP57|
|Target/Specificity||This CEP57 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-117 amino acids from the N-terminal region of human CEP57.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CEP57 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Centrosomal protein which may be required for microtubule attachment to centrosomes. May act by forming ring- like structures around microtubules. Mediates nuclear translocation and mitogenic activity of the internalized growth factor FGF2, but that of FGF1.|
|Cellular Location||Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Translokin binds basic fibroblast growth factor (FGF2; MIM 134920) and mediates its nuclear translocation and mitogenic activity (Bossard et al., 2003 [PubMed 12717444]).[supplied by OMIM].
Bailey, S.D., et al. Diabetes Care (2010) In press :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Petretti, C., et al. EMBO Rep. 7(4):418-424(2006)
Kim, Y.S., et al. Biol. Reprod. 70(1):106-113(2004)
Andersen, J.S., et al. Nature 426(6966):570-574(2003)
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