|Application ||WB, E|
|Other Accession||Q812D3, Q9D6L8, Q5ZLV2, NP_115861.1, NP_570981.1|
|Predicted||Chicken, Mouse, Rat|
|Calculated MW||18155 Da|
|Antigen Region||118-146 aa|
|Other Names||Peptidyl-prolyl cis-trans isomerase-like 3, PPIase, Cyclophilin J, CyPJ, Cyclophilin-like protein PPIL3, Rotamase PPIL3, PPIL3|
|Target/Specificity||This PPIL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-146 amino acids from the C-terminal region of human PPIL3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PPIL3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. May be involved in pre-mRNA splicing.|
|Tissue Location||Ubiquitous. Detected at low levels.|
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a member of the cyclophilin family. Cyclophilins catalyze the cis-trans isomerization of peptidylprolyl imide bonds in oligopeptides. They have been proposed to act either as catalysts or as molecular chaperones in protein-folding events. Alternative splicing results in multiple transcript variants.
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Huo, D.H., et al. Biochem. Biophys. Res. Commun. 372(1):14-18(2008)
Qi, Z.Y., et al. Chin. Med. J. 118(10):799-805(2005)
Hillier, L.W., et al. Nature 434(7034):724-731(2005)
Huang, L.L., et al. Acta Crystallogr. D Biol. Crystallogr. 61 (PT 3), 316-321 (2005) :
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