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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   TPPP Antibody (Center)   

TPPP Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - TPPP Antibody (Center) AP17081C
    TPPP Antibody (Center) (Cat. #AP17081c) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the TPPP antibody detected the TPPP protein (arrow).
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O94811
Other Accession NP_008961.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 23694 Da
Antigen Region 47-75 aa
Additional Information
Gene ID 11076
Other Names Tubulin polymerization-promoting protein, TPPP, 25 kDa brain-specific protein, TPPP/p25, p24, p25-alpha, TPPP, TPPP1
Target/Specificity This TPPP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 47-75 amino acids from the Central region of human TPPP.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTPPP Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TPPP
Synonyms TPPP1
Function May play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton. Nucleus. Note=Localizes to glial Lewy bodies in the brains of individuals with synucleinopathies
Tissue Location Widely expressed.
Research Areas
Citations (0)

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Background

TPPP may play a role in the polymerization of tubulin into microtubules, microtubule bundling and the stabilization of existing microtubules, thus maintaining the integrity of the microtubule network. May play a role in mitotic spindle assembly and nuclear envelope breakdown.

References

Tokesi, N., et al. J. Biol. Chem. 285(23):17896-17906(2010)
McGovern, D.P., et al. Nat. Genet. 42(4):332-337(2010)
Sun, M., et al. Cell. Signal. 21(12):1857-1865(2009)
Ovadi, J., et al. Bioessays 31(6):676-686(2009)
Zhou, Y., et al. Leuk. Lymphoma 49(10):1945-1953(2008)

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$ 295.00
$ 99.00
Cat# AP17081C
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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