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NDRG4 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - NDRG4 Antibody (Center) AP17090c
    NDRG4 Antibody (Center) (Cat. #AP17090c) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the NDRG4 antibody detected the NDRG4 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9ULP0
Other Accession Q9Z2L9, Q8BTG7, NP_001123959.1, NP_065198.1
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 38459 Da
Antigen Region 193-220 aa
Additional Information
Gene ID 65009
Other Names Protein NDRG4, Brain development-related molecule 1, N-myc downstream-regulated gene 4 protein, Vascular smooth muscle cell-associated protein 8, SMAP-8, NDRG4, BDM1, KIAA1180
Target/Specificity This NDRG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 193-220 amino acids from the Central region of human NDRG4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNDRG4 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NDRG4
Synonyms BDM1, KIAA1180
Function Contributes to the maintenance of intracerebral BDNF levels within the normal range, which is necessary for the preservation of spatial learning and the resistance to neuronal cell death caused by ischemic stress (By similarity). May enhance growth factor-induced ERK1 and ERK2 phosphorylation, including that induced by PDGF and FGF. May attenuate NGF-promoted ELK1 phosphorylation in a microtubule-dependent manner.
Cellular Location Cytoplasm, cytosol
Tissue Location Expressed predominantly in brain and heart (at protein level). In the brain, detected in astrocytes. Isoform 1 and isoform 2 are only expressed in brain. Isoform 3 is expressed in both heart and brain. Up-regulated in glioblastoma multiforme cells.
Research Areas
Citations (0)

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This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may be involved in the regulation of mitogenic signalling in vascular smooth muscles cells. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq].


Rose, J. Phd, et al. Mol. Med. (2010) In press :
Holm, H., et al. Nat. Genet. 42(2):117-122(2010)
Schilling, S.H., et al. J. Biol. Chem. 284(37):25160-25169(2009)
Melotte, V., et al. J. Natl. Cancer Inst. 101(13):916-927(2009)
Pfeufer, A., et al. Nat. Genet. 41(4):407-414(2009)

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$ 295.00
$ 99.00
Cat# AP17090c
(40 western blots)
Availability: In Stock
Bulk Size
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