- CITATIONS: 1
|Application ||FC, WB, E|
|Other Accession||Q9TT13, Q29380, Q60931, Q9MZ13, NP_005653.3, NP_001129166.1|
|Reactivity||Human, Mouse, Rat|
|Predicted||Bovine, Pig, Rabbit|
|Calculated MW||30659 Da|
|Antigen Region||156-183 aa|
|Other Names||Voltage-dependent anion-selective channel protein 3, VDAC-3, hVDAC3, Outer mitochondrial membrane protein porin 3, VDAC3|
|Target/Specificity||This VDAC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-183 amino acids from the Central region of human VDAC3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||VDAC3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.|
|Cellular Location||Mitochondrion outer membrane.|
|Tissue Location||Widely expressed. Highest in testis.|
Provided below are standard protocols that you may find useful for product applications.
VDAC3 belongs to a group of mitochondrial membrane channels involved in translocation of adenine nucleotides through the outer membrane. These channels may also function as a mitochondrial binding site for hexokinase (see HK1; MIM 142600) and glycerol kinase (GK; MIM 300474) (Rahmani et al., 1998).[supplied by OMIM].
Reina, S., et al. FEBS Lett. 584(13):2837-2844(2010)
Lefievre, L., et al. Proteomics 7(17):3066-3084(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
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