- CITATIONS: 1
|Application ||FC, WB, E|
|Other Accession||Q9TT13, Q29380, Q60931, Q9MZ13, NP_005653.3, NP_001129166.1|
|Reactivity||Human, Mouse, Rat|
|Predicted||Bovine, Pig, Rabbit|
|Calculated MW||30659 Da|
|Antigen Region||156-183 aa|
|Other Names||Voltage-dependent anion-selective channel protein 3, VDAC-3, hVDAC3, Outer mitochondrial membrane protein porin 3, VDAC3|
|Target/Specificity||This VDAC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-183 amino acids from the Central region of human VDAC3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||VDAC3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Forms a channel through the mitochondrial outer membrane that allows diffusion of small hydrophilic molecules.|
|Cellular Location||Mitochondrion outer membrane.|
|Tissue Location||Widely expressed. Highest in testis.|
Provided below are standard protocols that you may find useful for product applications.
VDAC3 belongs to a group of mitochondrial membrane channels involved in translocation of adenine nucleotides through the outer membrane. These channels may also function as a mitochondrial binding site for hexokinase (see HK1; MIM 142600) and glycerol kinase (GK; MIM 300474) (Rahmani et al., 1998).[supplied by OMIM].
Reina, S., et al. FEBS Lett. 584(13):2837-2844(2010)
Lefievre, L., et al. Proteomics 7(17):3066-3084(2007)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at email@example.com.