OSTF1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | Q92882 |
Other Accession | Q7ZYG4, Q6P686, Q8MJ49, Q62422, Q6TGW5, Q5ZJJ9, Q8MJ50, NP_036515.4 |
Reactivity | Human |
Predicted | Bovine, Chicken, Zebrafish, Mouse, Pig, Rat, Xenopus |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 23787 Da |
Antigen Region | 10-37 aa |
Gene ID | 26578 |
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Other Names | Osteoclast-stimulating factor 1, OSTF1 |
Target/Specificity | This OSTF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-37 amino acids from the N-terminal region of human OSTF1. |
Dilution | WB~~1:1000 |
Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | OSTF1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | OSTF1 |
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Function | Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity. |
Cellular Location | Cytoplasm. |
Tissue Location | Ubiquitously expressed. Present in osteoclasts (at protein level). |
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Provided below are standard protocols that you may find useful for product applications.
Background
Osteoclast-stimulating factor-1 is an intracellular protein produced by osteoclasts that indirectly induces osteoclast formation and bone resorption (Reddy et al., 1998 [PubMed 10092216]).
References
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Tong, S., et al. Proteins 75(1):245-251(2009)
Voss, M., et al. BMC Immunol. 10, 53 (2009) :
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
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