|Application ||WB, E|
|Other Accession||Q7ZYG4, Q6P686, Q8MJ49, Q62422, Q6TGW5, Q5ZJJ9, Q8MJ50, NP_036515.4|
|Predicted||Bovine, Chicken, Zebrafish, Mouse, Pig, Rat, Xenopus|
|Calculated MW||23787 Da|
|Antigen Region||10-37 aa|
|Other Names||Osteoclast-stimulating factor 1, OSTF1|
|Target/Specificity||This OSTF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-37 amino acids from the N-terminal region of human OSTF1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||OSTF1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Induces bone resorption, acting probably through a signaling cascade which results in the secretion of factor(s) enhancing osteoclast formation and activity.|
|Tissue Location||Ubiquitously expressed. Present in osteoclasts (at protein level).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Osteoclast-stimulating factor-1 is an intracellular protein produced by osteoclasts that indirectly induces osteoclast formation and bone resorption (Reddy et al., 1998 [PubMed 10092216]).
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
Yerges, L.M., et al. J. Bone Miner. Res. 24(12):2039-2049(2009)
Tong, S., et al. Proteins 75(1):245-251(2009)
Voss, M., et al. BMC Immunol. 10, 53 (2009) :
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
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