|Application ||WB, E|
|Other Accession||Q4EW11, NP_004239.1|
|Calculated MW||41121 Da|
|Antigen Region||284-312 aa|
|Other Names||Prolactin-releasing peptide receptor, PrRP receptor, PrRPR, G-protein coupled receptor 10, hGR3, PRLHR, GPR10, GR3|
|Target/Specificity||This PRLHR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 284-312 amino acids from the C-terminal region of human PRLHR.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PRLHR Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for prolactin-releasing peptide (PrRP). Implicated in lactation, regulation of food intake and pain-signal processing.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Only detected in the pituitary gland and in all cell types of pituitary adenomas|
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Provided below are standard protocols that you may find useful for product applications.
PRLHR is a 7-transmembrane domain receptor for prolactin-releasing hormone (PRLH; MIM 602663) that is highly expressed in anterior pituitary (Ozawa et al., 2002 [PubMed 11923475]).
Bailey, S.D., et al. Diabetes Care (2010) In press :
Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)
Lagerstrom, M.C., et al. Genomics 85(6):688-703(2005)
Ellacott, K.L., et al. Peptides 26(4):675-681(2005)
Deloukas, P., et al. Nature 429(6990):375-381(2004)
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