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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Bmp10 Antibody (N-term)   

Bmp10 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Bmp10 Antibody (N-term) AP1710a
    Western blot analysis of anti-Bmp10 Antibody (N-term) (Cat.#AP1710a) in 293 cell line lysates (35ug/lane). Bmp10(arrow) was detected using the purified Pab.
  • IHC-P - Bmp10 Antibody (N-term) AP1710a
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O95393
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 48047 Da
Antigen Region 7-35 aa
Additional Information
Gene ID 27302
Other Names Bone morphogenetic protein 10, BMP-10, BMP10
Target/Specificity This Bmp10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-35 amino acids from the N-terminal region of human Bmp10.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsBmp10 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BMP10
Function Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
Cellular Location Secreted.
Tissue Location Detected in mammary epithelia (at protein level).
Research Areas
Citations (0)

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BMP10 is a member of the TGF-beta family of growth factors. Data suggest that the similar protein in mouse plays an important role in trabeculation of the embryonic heart. In human, this protein may signal through receptor serine/threonine kinases.


Neuhaus, H., et al., Mech. Dev. 80(2):181-184 (1999).

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$ 295.00
$ 99.00
Cat# AP1710a
(40 western blots)
Availability: In Stock
Bulk Size
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