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KCNJ15 Antibody (C-term)

Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - KCNJ15 Antibody (C-term) AP17113B
    KCNJ15 Antibody (C-term) (Cat. #AP17113b) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the KCNJ15 antibody detected the KCNJ15 protein (arrow).
    detail
  • WB - KCNJ15 Antibody (C-term) AP17113B
    Anti-KCNJ15 Antibody (C-term) at 1:1000 dilution + human kidney lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 43 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q99712
Other Accession NP_733932.1, NP_002234.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit IgG
Calculated MW 42577 Da
Antigen Region 339-367 aa
Additional Information
Gene ID 3772
Other Names ATP-sensitive inward rectifier potassium channel 15, Inward rectifier K(+) channel Kir13, Inward rectifier K(+) channel Kir42, Potassium channel, inwardly rectifying subfamily J member 15, KCNJ15, KCNJ14
Target/Specificity This KCNJ15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 339-367 amino acids from the C-terminal region of human KCNJ15.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKCNJ15 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KCNJ15
Synonyms KCNJ14
Function Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.
Cellular Location Membrane; Multi-pass membrane protein.
Research Areas
Citations (0)
citation

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Background

Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Three transcript variants encoding the same protein have been found for this gene.

References

Okamoto, K., et al. Am. J. Hum. Genet. 86(1):54-64(2010)
Sindic, A., et al. Am. J. Physiol. Renal Physiol. 297 (1), F36-F45 (2009) :
Ji, W., et al. Nat. Genet. 40(5):592-599(2008)
Huang, C., et al. Am. J. Physiol. Renal Physiol. 292 (3), F1073-F1081 (2007) :
Kubo, Y., et al. Pharmacol. Rev. 57(4):509-526(2005)

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$ 182.50
$ 70.00
Cat# AP17113B
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