|Application ||WB, E|
|Other Accession||O35824, Q9QYJ0, Q2HJ94, NP_005871.1|
|Predicted||Bovine, Mouse, Rat|
|Calculated MW||45746 Da|
|Antigen Region||44-72 aa|
|Other Names||DnaJ homolog subfamily A member 2, Cell cycle progression restoration gene 3 protein, Dnj3, Dj3, HIRA-interacting protein 4, Renal carcinoma antigen NY-REN-14, DNAJA2, CPR3, HIRIP4|
|Target/Specificity||This DNAJA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 44-72 amino acids from the N-terminal region of human DNAJA2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DNAJA2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Co-chaperone of Hsc70.|
|Cellular Location||Membrane; Lipid-anchor|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene belongs to the evolutionarily conserved DNAJ/HSP40 family of proteins, which regulate molecular chaperone activity by stimulating ATPase activity. DNAJ proteins may have up to 3 distinct domains: a conserved 70-amino acid J domain, usually at the N terminus; a glycine/phenylalanine (G/F)-rich region; and a cysteine-rich domain containing 4 motifs resembling a zinc finger domain. The product of this gene works as a cochaperone of Hsp70s in protein folding and mitochondrial protein import in vitro.
Walker, V.E., et al. J. Biol. Chem. 285(5):3319-3329(2010)
Rosales-Hernandez, A., et al. Cell Stress Chaperones 14(1):71-82(2009)
Tzankov, S., et al. J. Biol. Chem. 283(40):27100-27109(2008)
Lamesch, P., et al. Genomics 89(3):307-315(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
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