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BMP15 Antibody (Center)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AP1711c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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BMP15 Antibody (Center) - Product info | |
| Application | WB, IHC
|
| Primary Accession | O95972 |
| Other Accession | NP_005439 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 45055 Da |
BMP15 Antibody (Center) - Additional info | |
| Gene ID 9210 | |
| Other Names BMP15; GDF9B; Bone morphogenetic protein 15; Growth/differentiation factor 9B | |
| Target/Specificity This BMP15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249~278 amino acids from the Center region of human BMP15. | |
| Dilution WB~~1:50~100WB~~1:1000 IHC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions BMP15 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
BMP15 Antibody (Center) - Protein Information | |
| Name BMP15 | |
| Synonyms GDF9B | |
| Function May be involved in follicular development. Oocyte- specific growth/differentiation factor that stimulates folliculogenesis and granulosa cell (GC) growth | |
| Cellular Location Secreted. | |
BMP15 Antibody (Center) - Related products
AP1711a: Bmp15 Antibody (N-term)
AP1711c: BMP15 Antibody (Center)
RI10610: BMP15 predesign siRNA
DC12350: Human BMP15 cDNA Clone
LY10630a: BMP15 Over-expression Lysate
BMP15 Antibody (Center) - Application data
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Western blot analysis of BMP15 Antibody (Center) (Cat. #AP1711c) in CEM cell line lysates (35ug/lane). BMP15 (arrow) was detected using the purified Pab.
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Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with BMP15 antibody (Center) (Cat.#AP1711c), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
BMP15 Antibody (Center) - Research Areas
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BACKGROUND
Bmp15 is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The transforming growth factor-beta superfamily includes large families of growth and differentiation factors. It is thought that Bmp15 may be involved in oocyte maturation and follicular development as a homodimer or by forming heterodimers with a related protein, Gdf9.
REFERENCES
Liao, W.X., et al., J. Biol. Chem. 278(6):3713-3719 (2003). Moore, R.K., et al., J. Biol. Chem. 278(1):304-310 (2003). Galloway, S.M., et al., Nat. Genet. 25(3):279-283 (2000). Aaltonen, J., et al., J. Clin. Endocrinol. Metab. 84(8):2744-2750 (1999). Dube, J.L., et al., Mol. Endocrinol. 12(12):1809-1817 (1998).