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FSD1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9BTV5 |
| Other Accession | NP_077309.1 |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 55820 Da |
| Antigen Region | 94-122 aa |
| Gene ID | 79187 |
|---|---|
| Other Names | Fibronectin type III and SPRY domain-containing protein 1, MID1-related protein 1, Microtubule-associated protein GLFND, FSD1, GLFND, MIR1 |
| Target/Specificity | This FSD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-122 amino acids from the N-terminal region of human FSD1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | FSD1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | FSD1 |
|---|---|
| Synonyms | GLFND, MIR1 |
| Function | May be involved in microtubule organization and stabilization. |
| Cellular Location | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Cytoplasm. Cleavage furrow. Note=Cell- cycle-dependent association with the centrosome. Colocalizes with a subpopulation of microtubules. Does not associate with microtubules during mitosis but reassociates with microtubules during cytokinesis Localizes to the central portions of a small subset of microtubules in interphase cells and a subpopulation of microtubules in the cleavage furrow, not present in the mitotic spindle |
| Tissue Location | Highly expressed in brain tissues, including cerebellum, cerebral cortex, medulla, occipital pole, frontal lobe, temporal lobe and putamen. Lower expression in spinal chord |
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a centrosome associated protein that is characterized by an N-terminal coiled-coil region downstream of B-box (BBC) domain, a central fibronectin type III domain, and a C-terminal repeats in splA and RyR (SPRY) domain. The encoded protein associates with a subset of microtubules and may be involved in the stability and organization of microtubules during cytokinesis.
References
Manabe, R., et al. Curr. Biol. 12(22):1946-1951(2002)
Stein, P.A., et al. J. Cell. Sci. 115 (PT 17), 3389-3402 (2002) :
Carim-Todd, L., et al. Biochim. Biophys. Acta 1518 (1-2), 200-203 (2001) :
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