|Application ||WB, E|
|Calculated MW||60861 Da|
|Antigen Region||103-130 aa|
|Other Names||Probable G-protein coupled receptor 97, G-protein coupled receptor PGR26, GPR97, PGR26|
|Target/Specificity||This GPR97 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-130 amino acids from the N-terminal region of human GPR97.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GPR97 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Orphan receptor that regulates migration of lymphatic endothelial cells in vitro via the small GTPases RhoA and CDC42 (PubMed:24178298). Regulates B-cell development (By similarity). Seems to signal through G-alpha(q)-proteins (PubMed:22575658).|
|Cellular Location||Cell membrane; Multi-pass membrane protein|
|Tissue Location||Expressed in cultured primary dermal lymphatic endothelial cells.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
GPR97 is an orphan receptor.
Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :
Bjarnadottir, T.K., et al. Genomics 84(1):23-33(2004)
Vassilatis, D.K., et al. Proc. Natl. Acad. Sci. U.S.A. 100(8):4903-4908(2003)
Fredriksson, R., et al. FEBS Lett. 531(3):407-414(2002)
Kuznicki, J., et al. Cell Biol. Int. Rep. 3(1):17-23(1979)
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