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KLHL3 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - KLHL3 Antibody (Center) AP17126c
    Anti-KLHL3 Antibody (Center) at 1:1000 dilution + HL-60 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 65kDa Blocking/Dilution buffer: 5% NFDM/TBST.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UH77
Other Accession F1MBP6, NP_059111.2
Reactivity Human
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 64970 Da
Antigen Region 207-234 aa
Additional Information
Gene ID 26249
Other Names Kelch-like protein 3, KLHL3, KIAA1129
Target/Specificity This KLHL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 207-234 amino acids from the Central region of human KLHL3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKLHL3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KLHL3
Synonyms KIAA1129
Function Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of ion transport in the distal nephron. The BCR(KLHL3) complex acts by mediating ubiquitination of WNK4, an inhibitor of potassium channel KCNJ1, leading to WNK4 degradation.
Cellular Location Cytoplasm, cytoskeleton. Cytoplasm, cytosol
Tissue Location Widely expressed.
Research Areas
Citations (0)

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Probable substrate-specific adapter of an E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.


Schmutz, J., et al. Nature 431(7006):268-274(2004)
Yeo, A., et al. J. Neurochem. 76(6):1688-1700(2001)
Lai, F., et al. Genomics 66(1):65-75(2000)
Mizutani, A., et al. J. Biol. Chem. 275(13):9823-9831(2000)

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$ 295.00
$ 99.00
Cat# AP17126c
(40 western blots)
Availability: In Stock
Bulk Size
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