ZFYVE27 Antibody (N-term)
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
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(40 western blots)
|In Stock||$ 265.00||Add to cart|
(8 western blots)
|In Stock||$ 95.00||Add to cart|
- Citations : 0
ZFYVE27 Antibody (N-term) - Product Information
|Other Accession||Q6P7B7, Q3TXX3, NP_001002261.1, NP_001002262.1|
|Calculated MW||45843 Da|
|Antigen Region||28-56 aa|
ZFYVE27 Antibody (N-term) - Additional Information
|Gene ID 118813|
Protrudin, Zinc finger FYVE domain-containing protein 27, ZFYVE27
This ZFYVE27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 28-56 amino acids from the N-terminal region of human ZFYVE27.
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
ZFYVE27 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
ZFYVE27 Antibody (N-term) - Protein Information
Functions as an upstream inhibitor of RAB11, regulating directional protein transport to the forming neurites. Involved in nerve growth factor-induced neurite formation. May have a more general role in cell projections formation.
Recycling endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell projection, growth cone membrane; Multi- pass membrane protein. Cell membrane; Multi-pass membrane protein Note=Localizes at both dendrites and axons.
ZFYVE27 Antibody (N-term) - Related Products
ZFYVE27 Antibody (N-term) - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear.
Saita, S., et al. J. Biol. Chem. 284(20):13766-13777(2009)
Martignoni, M., et al. Am. J. Hum. Genet. 83(1):127-128(2008)
Shirane, M., et al. Science 314(5800):818-821(2006)
Mannan, A.U., et al. Am. J. Hum. Genet. 79(2):351-357(2006)
Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)