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ZFYVE27 Antibody (N-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP17130a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP17130a-ev20 | Ev20 size 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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ZFYVE27 Antibody (N-term) - Product info | |
| Application | WB
|
| Primary Accession | Q5T4F4 |
| Other Accession | Q6P7B7, Q3TXX3, NP_001002261.1, NP_001002262.1 |
| Reactivity | Human |
| Predicted | Mouse, Rat |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 45843 Da |
ZFYVE27 Antibody (N-term) - Additional info | |
| Gene ID 118813 | |
| Other Names ZFYVE27; Protrudin; Zinc finger FYVE domain-containing protein 27 | |
| Target/Specificity This ZFYVE27 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 27-56 amino acids from the N-terminal region of human ZFYVE27. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ZFYVE27 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ZFYVE27 Antibody (N-term) - Protein Information | |
| Name ZFYVE27 | |
| Function Functions as an upstream inhibitor of RAB11, regulating directional protein transport to the forming neurites. Involved in nerve growth factor-induced neurite formation. May have a more general role in cell projections formation | |
| Cellular Location Recycling endosome membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell projection, growth cone membrane; Multi- pass membrane protein. Cell membrane; Multi-pass membrane protein Note=Localizes at both dendrites and axons (By similarity) | |
ZFYVE27 Antibody (N-term) - Related products
ZFYVE27 Antibody (N-term) - Application data
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ZFYVE27 Antibody (N-term) (Cat. #AP17130a) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the ZFYVE27 antibody detected the ZFYVE27 protein (arrow).
ZFYVE27 Antibody (N-term) - Research Areas
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BACKGROUND
This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear.
REFERENCES
Saita, S., et al. J. Biol. Chem. 284(20):13766-13777(2009) Martignoni, M., et al. Am. J. Hum. Genet. 83(1):127-128(2008) Shirane, M., et al. Science 314(5800):818-821(2006) Mannan, A.U., et al. Am. J. Hum. Genet. 79(2):351-357(2006) Wang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)
