|Application ||WB, E|
|Other Accession||NP_001025147.2, NP_008889.2|
|Calculated MW||76472 Da|
|Antigen Region||53-81 aa|
|Other Names||Zinc finger protein 16, Zinc finger protein KOX9, ZNF16, HZF1, KOX9|
|Target/Specificity||This ZNF16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-81 amino acids from the N-terminal region of human ZNF16.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ZNF16 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a transcriptional activator. Promotes cell proliferation by facilitating the cell cycle phase transition from the S to G2/M phase. Involved in both the hemin- and phorbol myristate acetate (PMA)-induced erythroid and megakaryocytic differentiation, respectively. Plays also a role as an inhibitor of cell apoptosis.|
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Provided below are standard protocols that you may find useful for product applications.
The protein encoded by this gene contains a C2H2 type of zinc finger, and thus may function as a transcription factor. This gene is located in a region close to ZNF7/KOX4, a gene also encoding a zinc finger protein, on chromosome 8. Two alternatively spliced variants, encoding the same protein, have been identified.
Dreier, B., et al. J. Mol. Biol. 303(4):489-502(2000)
Rousseau-Merck, M.F., et al. Ann. Genet. 38(2):81-84(1995)
Thiesen, H.J. New Biol. 2(4):363-374(1990)
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