|Application ||WB, E|
|Calculated MW||21211 Da|
|Antigen Region||98-127 aa|
|Other Names||T-cell receptor-associated transmembrane adapter 1, T-cell receptor-interacting molecule, TRIM, pp29/30, TRAT1, TCRIM|
|Target/Specificity||This TRAT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-127 amino acids from the Central region of human TRAT1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TRAT1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.|
|Cellular Location||Cell membrane; Single-pass type III membrane protein|
|Tissue Location||Strongly expressed in thymus, and to a lesser extent in spleen, lymph node and peripheral blood lymphocytes Present in T-cells and NK cells, but not B-cells (at protein level).|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
TRAT1 stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.
Jarvis, L.B., et al. Hum. Immunol. 69(11):687-695(2008)
Tedoldi, S., et al. Blood 107(1):213-221(2006)
Koyasu, S. Nat. Immunol. 4(4):313-319(2003)
Kirchgessner, H., et al. J. Exp. Med. 193(11):1269-1284(2001)
Zhang, W., et al. Semin. Immunol. 12(1):35-41(2000)
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