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GCNT1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GCNT1 Antibody (Center) AP17151c
    GCNT1 Antibody (Center) (Cat. #AP17151c) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the GCNT1 antibody detected the GCNT1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q02742
Other Accession NP_001091103.1, NP_001091102.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 49799 Da
Antigen Region 63-91 aa
Additional Information
Gene ID 2650
Other Names Beta-1, 3-galactosyl-O-glycosyl-glycoprotein beta-1, 6-N-acetylglucosaminyltransferase, Core 2-branching enzyme, Core2-GlcNAc-transferase, C2GNT, Core 2 GNT, GCNT1, NACGT2
Target/Specificity This GCNT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-91 amino acids from the Central region of human GCNT1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGCNT1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GCNT1
Synonyms NACGT2
Function Glycosyltransferase that catalyzes the transfer of an N- acetylglucosamine moiety onto mucin-type core 1 O-glycan to form the branched mucin-type core 2 O-glycan. Mucin-type core 2 O- glycans play an important role in leukocyte extravasation as they serve as scaffolds for the display of the selectin ligand sialyl Lewis X by leukocytes.
Cellular Location Golgi apparatus membrane; Single-pass type II membrane protein. Note=Also detected in the trans-Golgi network
Tissue Location Highly expressed in activated T-lymphocytes and myeloid cells
Research Areas
Citations (0)

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This gene is a member of the beta-1,6-N-acetylglucosaminyltransferase gene family. It is essential to the formation of Gal beta 1-3(GlcNAc beta 1-6)GalNAc structures and the core 2 O-glycan branch. The gene coding this enzyme was originally mapped to 9q21, but was later localized to 9q13. Multiple alternatively spliced variants, encoding the same protein, have been identified.


Hatakeyama, S., et al. Int. J. Cancer 127(5):1052-1059(2010)
Brockhausen, I., et al. Biochim. Biophys. Acta 1790(10):1244-1257(2009)
St Hill, C.A., et al. BMC Cancer 9, 79 (2009) :
Nagaraj, S., et al. Pancreas 37(3):321-327(2008)
Julien, S., et al. J. Immunol. 179(9):5701-5710(2007)

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$ 295.00
$ 99.00
Cat# AP17151c
(40 western blots)
Availability: In Stock
Bulk Size
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