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AKIRIN2 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - AKIRIN2 Antibody (C-term) AP17163b
    AKIRIN2 Antibody (C-term) (Cat. #AP17163b) western blot analysis in U937 cell line lysates (35ug/lane).This demonstrates the AKIRIN2 antibody detected the AKIRIN2 protein (arrow).
  • WB - AKIRIN2 Antibody (C-term) AP17163b
    Western blot analysis of AKIRIN2 (arrow) using rabbit polyclonal AKIRIN2 Antibody (C-term) (Cat. #AP17163b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the AKIRIN2 gene.
  • SPECIFICATION
  • CITATIONS
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q53H80
Other Accession Q25C79, B1AXD8, A8YXY8, NP_060534.1
Reactivity Human
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 22496 Da
Antigen Region 177-203 aa
Additional Information
Gene ID 55122
Other Names Akirin-2, AKIRIN2, C6orf166
Target/Specificity This AKIRIN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-203 amino acids from the C-terminal region of human AKIRIN2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAKIRIN2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name AKIRIN2
Synonyms C6orf166
Function Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1 (By similarity).
Cellular Location Nucleus.
Tissue Location Widely expressed with the highest expression in peripheral blood leukocytes.
Research Areas
Citations (0)

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Background

Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1 (By similarity).

References

Komiya, Y., et al. J. Biol. Chem. 283(27):18753-18764(2008)
Goto, A., et al. Nat. Immunol. 9(1):97-104(2008)
Levy, D., et al. BMC Med. Genet. 8 SUPPL 1, S3 (2007) :
Vasan, R.S., et al. BMC Med. Genet. 8 SUPPL 1, S2 (2007) :
Olsen, J.V., et al. Cell 127(3):635-648(2006)

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$ 295.00
$ 99.00
Cat# AP17163b
Size:
Quantity:
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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