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AKIRIN2 Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP17163b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP17163b-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
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- Backgrounds
AKIRIN2 Antibody (C-term) - Product info | |
| Application | WB
|
| Primary Accession | Q53H80 |
| Other Accession | Q25C79, B1AXD8, A8YXY8, NP_060534.1 |
| Reactivity | Human |
| Predicted | Bovine, Mouse, Rat |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 22496 Da |
AKIRIN2 Antibody (C-term) - Additional info | |
| Gene ID 55122 | |
| Other Names AKIRIN2; C6orf166; Akirin-2 | |
| Target/Specificity This AKIRIN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 176-203 amino acids from the C-terminal region of human AKIRIN2. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions AKIRIN2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
AKIRIN2 Antibody (C-term) - Protein Information | |
| Name AKIRIN2 | |
| Synonyms C6orf166 | |
| Function Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1 (By similarity) | |
| Cellular Location Nucleus. | |
| Tissue Location Widely expressed with the highest expression in peripheral blood leukocytes | |
AKIRIN2 Antibody (C-term) - Related products
AP17163b: AKIRIN2 Antibody (C-term)
AKIRIN2 Antibody (C-term) - Application data
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AKIRIN2 Antibody (C-term) (Cat. #AP17163b) western blot analysis in U937 cell line lysates (35ug/lane).This demonstrates the AKIRIN2 antibody detected the AKIRIN2 protein (arrow).
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Western blot analysis of AKIRIN2 (arrow) using rabbit polyclonal AKIRIN2 Antibody (C-term) (Cat. #AP17163b). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the AKIRIN2 gene.
AKIRIN2 Antibody (C-term) - Research Areas
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BACKGROUND
Required for the innate immune response. Downstream effector of the Toll-like receptor (TLR), TNF and IL-1 beta signaling pathways leading to the production of IL-6. Forms a complex with YWHAB that acts to repress transcription of DUSP1 (By similarity).
REFERENCES
Komiya, Y., et al. J. Biol. Chem. 283(27):18753-18764(2008) Goto, A., et al. Nat. Immunol. 9(1):97-104(2008) Levy, D., et al. BMC Med. Genet. 8 SUPPL 1, S3 (2007) : Vasan, R.S., et al. BMC Med. Genet. 8 SUPPL 1, S2 (2007) : Olsen, J.V., et al. Cell 127(3):635-648(2006)
