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TBX20 Antibody (C-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9UMR3 |
| Other Accession | NP_001159692.1 |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 49232 Da |
| Antigen Region | 308-335 aa |
| Gene ID | 57057 |
|---|---|
| Other Names | T-box transcription factor TBX20, T-box protein 20, TBX20 |
| Target/Specificity | This TBX20 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-335 amino acids from the C-terminal region of human TBX20. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TBX20 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TBX20 |
|---|---|
| Function | Acts as a transcriptional activator and repressor required for cardiac development and may have key roles in the maintenance of functional and structural phenotypes in adult heart. |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00201}. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a T-box family member. The T-box family members share a common DNA binding domain, termed the T-box, and they are transcription factors involved in the regulation of developmental processes. This gene is essential for heart development. Mutations in this gene are associated with diverse cardiac pathologies, including defects in septation, valvulogenesis and cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
References
Ichikawa, S., et al. J. Bone Miner. Res. 25(8):1821-1829(2010)
Posch, M.G., et al. J. Med. Genet. 47(4):230-235(2010)
Macindoe, I., et al. J. Mol. Biol. 389(3):606-618(2009)
Liu, C., et al. Eur J Med Genet 51(6):580-587(2008)
Hammer, S., et al. J. Cell. Biochem. 104(3):1022-1033(2008)
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