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NUDT4 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - NUDT4 Antibody (N-term) AP17167a
    NUDT4 Antibody (N-term) (Cat. #AP17167a) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the NUDT4 antibody detected the NUDT4 protein (arrow).
  • WB - NUDT4 Antibody (N-term) AP17167a
    NUDT4 Antibody (N-term) (Cat. #AP17167a) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the NUDT4 antibody detected the NUDT4 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NZJ9
Other Accession Q99MY2, Q8R2U6, NP_950241.1
Reactivity Human, Mouse
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 20306 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 11163
Other Names Diphosphoinositol polyphosphate phosphohydrolase 2, DIPP-2, Diadenosine 5', 5'''-P1, P6-hexaphosphate hydrolase 2, 361-, Nucleoside diphosphate-linked moiety X motif 4, Nudix motif 4, NUDT4, DIPP2, KIAA0487
Target/Specificity This NUDT4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human NUDT4.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsNUDT4 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NUDT4
Synonyms DIPP2, KIAA0487
Function Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), PP-InsP4 and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphate Ap6A, but not Ap5A. The major reaction products are ADP and p4a from Ap6A. Also able to hydrolyze 5-phosphoribose 1-diphosphate. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA.
Cellular Location Cytoplasm.
Tissue Location Expressed in heart and, at lower level in skeletal muscle, pancreas and kidney
Research Areas
Citations (0)

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The protein encoded by this gene regulates the turnover of diphosphoinositol polyphosphates. The turnover of these high-energy diphosphoinositol polyphosphates represents a molecular switching activity with important regulatory consequences. Molecular switching by diphosphoinositol polyphosphates may contribute to regulating intracellular trafficking. Several alternatively spliced transcript variants have been described, but the full-length nature of some variants has not been determined. Isoforms DIPP2alpha and DIPP2beta are distinguishable from each other solely by DIPP2beta possessing one additional amino acid due to intron boundary skidding in alternate splicing.


Fortna, A., et al. PLoS Biol. 2 (7), E207 (2004) :
Fisher, D.I., et al. J. Biol. Chem. 277(49):47313-47317(2002)
Leslie, N.R., et al. BMC Biochem. 3, 20 (2002) :
Caffrey, J.J., et al. Gene 269 (1-2), 53-60 (2001) :
Caffrey, J.J., et al. J. Biol. Chem. 275(17):12730-12736(2000)

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$ 295.00
$ 99.00
Cat# AP17167a
(40 western blots)
Availability: In Stock
Bulk Size
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