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Bmp7 Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - Bmp7 Antibody (N-term) AP1718a
    Western blot analysis of Bmp7 (arrow) using rabbit polyclonal Bmp7 Antibody (N-term) (Cat.#AP1718a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the Bmp7 gene (Lane 2) (Origene Technologies).
  • IHC-P - Bmp7 Antibody (N-term) AP1718a
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
  • IF - Bmp7 Antibody (N-term) AP1718a
    Immunofluorescence analysis of Bmp7 Antibody (N-term) (Cat.#AP1718a) in HeLa cells. 0.025 mg/ml primary antibody was followed by Alexa-Fluor-546-conjugated donkey anti-rabbit lgG (H+L). Alexa-Fluor-546 emits orange fluorescence. Blue counterstaining is DAPI.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P18075
Other Accession P23359, NP_001710
Reactivity Human
Predicted Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 49313 Da
Antigen Region 15-44 aa
Additional Information
Gene ID 655
Other Names Bone morphogenetic protein 7, BMP-7, Osteogenic protein 1, OP-1, Eptotermin alfa, BMP7, OP1
Target/Specificity This Bmp7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-44 amino acids from the N-terminal region of human Bmp7.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsBmp7 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BMP7
Synonyms OP1
Function Induces cartilage and bone formation. May be the osteoinductive factor responsible for the phenomenon of epithelial osteogenesis. Plays a role in calcium regulation and bone homeostasis.
Cellular Location Secreted.
Tissue Location Expressed in the kidney and bladder. Lower levels seen in the brain
Research Areas
Citations ( 0 )


The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, BMP7 has a proposed role in early development. In addition, the fact that BMP7 is closely related to BMP5 and BMP6 has lead to speculation of possible bone inductive activity.


Merrihew, C., et al., J. Orthop. Res. 21(5):899-907 (2003).
Greenwald, J., et al., Mol. Cell 11(3):605-617 (2003).
Maric, I., et al., J. Cell. Physiol. 196(2):258-264 (2003).
Im, H.J., et al., J. Biol. Chem. 278(28):25386-25394 (2003).
Lee, M.J., et al., J. Immunol. 170(5):2557-2563 (2003).

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$ 295.00
$ 99.00
Cat# AP1718a
(40 western blots)
Availability: In Stock
Bulk Size
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