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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PPP1R13B Antibody (Center)   

PPP1R13B Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PPP1R13B Antibody (Center) AP17200C
    PPP1R13B Antibody (Center) (Cat. #AP17200c) western blot analysis in SK-BR-3 cell line lysates (35ug/lane).This demonstrates the PPP1R13B antibody detected the PPP1R13B protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96KQ4
Other Accession NP_056131.2
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 119565 Da
Antigen Region 623-652 aa
Additional Information
Gene ID 23368
Other Names Apoptosis-stimulating of p53 protein 1, Protein phosphatase 1 regulatory subunit 13B, PPP1R13B, ASPP1, KIAA0771
Target/Specificity This PPP1R13B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 623-652 amino acids from the Central region of human PPP1R13B.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPPP1R13B Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PPP1R13B
Synonyms ASPP1, KIAA0771
Function Regulator that plays a central role in regulation of apoptosis via its interaction with p53/TP53. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo.
Cellular Location Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Some fraction is nuclear
Tissue Location Reduced expression in breast carcinomas expressing a wild-type TP53 protein
Research Areas
Citations (0)

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This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.


Figl, A., et al. Mutat. Res. 702(1):8-16(2010)
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Zhao, J., et al. Hepatology 51(1):142-153(2010)
Agirre, X., et al. Oncogene 25(13):1862-1870(2006)
Liu, Z.J., et al. Biochim. Biophys. Acta 1756(1):77-80(2005)

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$ 295.00
$ 99.00
Cat# AP17200C
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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