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RBMS1 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AP17208c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP17208c-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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RBMS1 Antibody (Center) - Product info | |
| Application | WB
|
| Primary Accession | P29558 |
| Other Accession | NP_002888.1, NP_058520.1 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 44505 Da |
RBMS1 Antibody (Center) - Additional info | |
| Gene ID 5937 | |
| Other Names RBMS1; C2orf12; MSSP; MSSP1; SCR2; RNA-binding motif, single-stranded-interacting protein 1; Single-stranded DNA-binding protein MSSP-1; Suppressor of CDC2 with RNA-binding motif 2 | |
| Target/Specificity This RBMS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-252 amino acids from the Central region of human RBMS1. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions RBMS1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
RBMS1 Antibody (Center) - Protein Information | |
| Name RBMS1 | |
| Synonyms C2orf12, MSSP, MSSP1, SCR2 | |
| Function Single-stranded DNA binding protein that interacts with the region upstream of the MYC gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication | |
| Cellular Location Nucleus. | |
| Tissue Location Highest amounts are found in placenta, lung and heart | |
RBMS1 Antibody (Center) - Related products
AP17208c: RBMS1 Antibody (Center)
RI14483: RBMS1 predesign siRNA
RBMS1 Antibody (Center) - Application data
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RBMS1 Antibody (Center) (Cat. #AP17208c) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the RBMS1 antibody detected the RBMS1 protein (arrow).
RBMS1 Antibody (Center) - Research Areas
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BACKGROUND
This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12.
REFERENCES
Qi, L., et al. Hum. Mol. Genet. 19(13):2706-2715(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Landers, J.E., et al. Proc. Natl. Acad. Sci. U.S.A. 106(22):9004-9009(2009) Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007) Lamesch, P., et al. Genomics 89(3):307-315(2007)