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RBMS1 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Country
United States
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Ordering Information
Catalog # Size Availability Price  
AP17208c 0.1 mg 400 ul In Stock $ 255.00 Add to cart
AP17208c-ev20 20 ug 100 ul In Stock $ 95.00 Add to cart
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RBMS1 Antibody (Center) - Product info

ApplicationWB
  • Applications Legend:
  • W=Western Blotting
  • IP=Immunoprecipitation
  • IHC-P=Immunohistochemistry (Paraffin)
  • IF-IC=Immunofluorescence (Immunocytochemistry)
  • F=Flow Cytometry
Primary AccessionP29558
Other AccessionNP_002888.1, NP_058520.1
ReactivityHuman
Concentration0.25 mg/ml
IsotypeRabbit Ig
Calculated MW44505 Da

RBMS1 Antibody (Center) - Additional info

Gene ID 5937
Other Names
RBMS1; C2orf12; MSSP; MSSP1; SCR2; RNA-binding motif, single-stranded-interacting protein 1; Single-stranded DNA-binding protein MSSP-1; Suppressor of CDC2 with RNA-binding motif 2
Target/Specificity
This RBMS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 223-252 amino acids from the Central region of human RBMS1.
Dilution
WB~~1:100~500
Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage
Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautions
RBMS1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.

RBMS1 Antibody (Center) - Protein Information

Name RBMS1
Synonyms C2orf12, MSSP, MSSP1, SCR2
Function
Single-stranded DNA binding protein that interacts with the region upstream of the MYC gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication
Cellular Location
Nucleus.
Tissue Location
Highest amounts are found in placenta, lung and heart

RBMS1 Antibody (Center) - Related products

AP17208c: RBMS1 Antibody (Center)

RI14483: RBMS1 predesign siRNA

AT3595a: RBMS1 Antibody (monoclonal) (M01)

AT3596a: RBMS1 Antibody (monoclonal) (M02)

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BACKGROUND

This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12.

REFERENCES

Qi, L., et al. Hum. Mol. Genet. 19(13):2706-2715(2010) Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Landers, J.E., et al. Proc. Natl. Acad. Sci. U.S.A. 106(22):9004-9009(2009) Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007) Lamesch, P., et al. Genomics 89(3):307-315(2007)