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UBE2V2 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - UBE2V2 Antibody (Center) AP17212c
    UBE2V2 Antibody (Center) (Cat. #AP17212c) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the UBE2V2 antibody detected the UBE2V2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15819
Other Accession Q7M767, Q9D2M8, Q3SZ43, NP_003341.1
Reactivity Human
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 16363 Da
Antigen Region 75-104 aa
Additional Information
Gene ID 7336
Other Names Ubiquitin-conjugating enzyme E2 variant 2, DDVit 1, Enterocyte differentiation-associated factor 1, EDAF-1, Enterocyte differentiation-promoting factor 1, EDPF-1, MMS2 homolog, Vitamin D3-inducible protein, UBE2V2, MMS2, UEV2
Target/Specificity This UBE2V2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-104 amino acids from the Central region of human UBE2V2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsUBE2V2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UBE2V2
Synonyms MMS2, UEV2
Function Has no ubiquitin ligase activity on its own. The UBE2V2/UBE2N heterodimer catalyzes the synthesis of non-canonical poly-ubiquitin chains that are linked through 'Lys-63'. This type of poly-ubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage.
Tissue Location Detected in placenta, colon, liver and skin. Detected at very low levels in most tissues
Research Areas
Citations (0)

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Ubiquitin-conjugating enzyme E2 variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene also shares homology with ubiquitin-conjugating enzyme E2 variant 1 and yeast MMS2 gene product. It may be involved in the differentiation of monocytes and enterocytes.


Wen, R., et al. Plant Cell 20(1):213-227(2008)
Brun, J., et al. BMC Mol. Biol. 9, 24 (2008) :
Pastushok, L., et al. FEBS Lett. 581(28):5343-5348(2007)
Zhao, G.Y., et al. Mol. Cell 25(5):663-675(2007)
Wen, R., et al. Plant Mol. Biol. 61 (1-2), 241-253 (2006) :

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Cat# AP17212c
(40 western blots)
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