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FPR1 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - FPR1 Antibody (Center) AP17216c
    FPR1 Antibody (Center) (Cat. #AP17216c) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the FPR1 antibody detected the FPR1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P21462
Other Accession NP_002020.1, NP_001180235.1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 38446 Da
Antigen Region 165-193 aa
Additional Information
Gene ID 2357
Other Names fMet-Leu-Phe receptor, fMLP receptor, N-formyl peptide receptor, FPR, N-formylpeptide chemoattractant receptor, FPR1
Target/Specificity This FPR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-193 amino acids from the Central region of human FPR1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFPR1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FPR1
Function High affinity receptor for N-formyl-methionyl peptides (fMLP), which are powerful neutrophil chemotactic factors (PubMed:2161213, PubMed:2176894, PubMed:10514456, PubMed:15153520). Binding of fMLP to the receptor stimulates intracellular calcium mobilization and superoxide anion release (PubMed:2161213, PubMed:1712023, PubMed:15153520). This response is mediated via a G-protein that activates a phosphatidylinositol- calcium second messenger system (PubMed:1712023, PubMed:10514456).
Cellular Location Cell membrane; Multi- pass membrane protein
Tissue Location Neutrophils.
Research Areas
Citations (0)

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This gene encodes a G protein-coupled receptor of mammalian phagocytic cells that is a member of the G-protein coupled receptor 1 family. The protein mediates the response of phagocytic cells to invasion of the host by microorganisms and is important in host defense and inflammation.


Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Huang, J., et al. Br. J. Cancer 102(6):1052-1060(2010)
Segat, L., et al. Vaccine 28(10):2201-2206(2010)
Zhu, X.L., et al. Beijing Da Xue Xue Bao 41(6):664-668(2009)
Kobayashi, T., et al. J. Dent. Res. 88(12):1137-1141(2009)

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$ 295.00
$ 99.00
Cat# AP17216c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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