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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   PJA2 Antibody (Center)   

PJA2 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PJA2 Antibody (Center) AP17220c
    PJA2 Antibody (Center) (Cat. #AP17220c) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the PJA2 antibody detected the PJA2 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O43164
Other Accession NP_055634.3
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 78214 Da
Antigen Region 284-311 aa
Additional Information
Gene ID 9867
Other Names E3 ubiquitin-protein ligase Praja-2, Praja2, 632-, RING finger protein 131, PJA2, KIAA0438, RNF131
Target/Specificity This PJA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 284-311 amino acids from the Central region of human PJA2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPJA2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PJA2
Synonyms KIAA0438, RNF131
Function Has E2-dependent E3 ubiquitin-protein ligase activity. Responsible for ubiquitination of cAMP-dependent protein kinase type I and type II-alpha/beta regulatory subunits and for targeting them for proteasomal degradation. Essential for PKA- mediated long-term memory processes.
Cellular Location Cytoplasm. Cell membrane. Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus membrane; Peripheral membrane protein. Cell junction, synapse. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Note=Localizes at the cytoplasmic side of endoplasmic reticulum and Golgi apparatus Expressed in the postsynaptic density region of synapses (By similarity). Colocalizes with PRKAR2A and PRKAR2B in the cytoplasm and the cell membrane.
Research Areas
Citations (0)

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PJA2 has E2-dependent E3 ubiquitin-protein ligase activity (By similarity).


Olsen, J.V., et al. Cell 127(3):635-648(2006)
Sasaki, A., et al. J. Biol. Chem. 277(25):22541-22546(2002)
Yu, P., et al. Genomics 79(6):869-874(2002)
Mishra, L., et al. Oncogene 15(19):2361-2368(1997)
Nakayama, M., et al. J. Neurosci. 15 (7 PT 2), 5238-5248 (1995) :

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$ 295.00
$ 99.00
Cat# AP17220c
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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