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KCNJ10 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - KCNJ10 Antibody (Center) AP17230c
    Anti-KCNJ10 Antibody (Center)at 1:2000 dilution + rat brain lysates Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution Predicted band size : 43 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - KCNJ10 Antibody (Center) AP17230c
    KCNJ10 Antibody (Center) (Cat. #AP17230c) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the KCNJ10 antibody detected the KCNJ10 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P78508
Other Accession P49655, Q9JM63, NP_002232.2
Reactivity Human
Predicted Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 42508 Da
Antigen Region 203-230 aa
Additional Information
Gene ID 3766
Other Names ATP-sensitive inward rectifier potassium channel 10, ATP-dependent inwardly rectifying potassium channel Kir41, Inward rectifier K(+) channel Kir12, Potassium channel, inwardly rectifying subfamily J member 10, KCNJ10
Target/Specificity This KCNJ10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-230 amino acids from the Central region of human KCNJ10.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKCNJ10 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name KCNJ10
Function May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity).
Cellular Location Membrane; Multi-pass membrane protein.
Research Areas
Citations (0)

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This gene encodes a member of the inward rectifier-type potassium channel family, characterized by having a greater tendency to allow potassium to flow into, rather than out of, a cell. The encoded protein may form a heterodimer with another potassium channel protein and may be responsible for the potassium buffering action of glial cells in the brain. Mutations in this gene have been associated with seizure susceptibility of common idiopathic generalized epilepsy syndromes.


Jonard, L., et al. Int. J. Pediatr. Otorhinolaryngol. 74(9):1049-1053(2010)
Reichold, M., et al. Proc. Natl. Acad. Sci. U.S.A. 107(32):14490-14495(2010)
Heuser, K., et al. Epilepsy Res. 88(1):55-64(2010)
Pawelczyk, M., et al. Ann. Hum. Genet. 73 (PT 4), 411-421 (2009) :
Yang, T., et al. Am. J. Hum. Genet. 84(5):651-657(2009)

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$ 295.00
$ 99.00
Cat# AP17230c
(40 western blots)
Availability: In Stock
Bulk Size
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