|Application ||WB, E|
|Other Accession||O08848, NP_001035828.1, NP_001166995.1|
|Calculated MW||60671 Da|
|Antigen Region||467-495 aa|
|Other Names||60 kDa SS-A/Ro ribonucleoprotein, 60 kDa Ro protein, 60 kDa ribonucleoprotein Ro, RoRNP, Ro 60 kDa autoantigen, Sjoegren syndrome antigen A2, Sjoegren syndrome type A antigen, SS-A, TROVE domain family member 2, TROVE2, RO60, SSA2|
|Target/Specificity||This TROVE2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 467-495 amino acids from the C-terminal region of human TROVE2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TROVE2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. May stabilize some of these RNAs and protect them from degradation.|
|Cellular Location||Cytoplasm. Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs|
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Provided below are standard protocols that you may find useful for product applications.
RNA-binding protein that binds to several small cytoplasmic RNA molecules known as Y RNAs. May stabilize these RNAs from degradation.
Reed, J.H., et al. Arthritis Rheum. 62(5):1448-1456(2010)
Davila, S., et al. Genes Immun. 11(3):232-238(2010)
Clancy, R.M., et al. J. Immunol. 184(4):2148-2155(2010)
Reed, J.H., et al. Arthritis Rheum. 60(3):860-869(2009)
Barcellos, K.S., et al. J. Rheumatol. 34(6):1283-1292(2007)
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