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OS9 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - OS9 Antibody (C-term) AP17237B
    OS9 Antibody (C-term) (Cat. #AP17237b) western blot analysis in U937 cell line lysates (35ug/lane).This demonstrates the OS9 antibody detected the OS9 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13438
Other Accession Q3MHX6, NP_001017958.1, NP_006803.1
Reactivity Human
Predicted Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 75562 Da
Antigen Region 521-549 aa
Additional Information
Gene ID 10956
Other Names Protein OS-9, Amplified in osteosarcoma 9, OS9
Target/Specificity This OS9 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 521-549 amino acids from the C-terminal region of human OS9.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsOS9 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name OS9
Function Lectin which functions in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD). May bind terminally misfolded non-glycosylated proteins as well as improperly folded glycoproteins, retain them in the ER, and possibly transfer them to the ubiquitination machinery and promote their degradation. Possible targets include TRPV4.
Cellular Location Endoplasmic reticulum lumen
Tissue Location Ubiquitously expressed. Found as well in all tumor cell lines analyzed, amplified in sarcomas. Highly expressed in osteosarcoma SJSA-1 and rhabdomyosarcoma Rh30 cell lines Isoform 2 is the major isoform detected in all cell types examined
Research Areas
Citations (0)

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This gene encodes a protein that is highly expressed in osteosarcomas. This protein binds to the hypoxia-inducible factor 1 (HIF-1), a key regulator of the hypoxic response and angiogenesis, and promotes the degradation of one of its subunits. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.


Feng, T., et al. Hum. Genet. 128(3):269-280(2010)
Mikami, K., et al. Glycobiology 20(3):310-321(2010)
Hosokawa, N., et al. J. Biol. Chem. 284(25):17061-17068(2009)
Jansen, B.J., et al. Mol. Immunol. 46(4):505-515(2009)
Alcock, F., et al. J. Mol. Biol. 385(4):1032-1042(2009)

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$ 295.00
$ 99.00
Cat# AP17237B
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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