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DDX21 Antibody (N-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP17238a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP17238a-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
DDX21 Antibody (N-term) - Product info | |
| Application | WB
|
| Primary Accession | Q9NR30 |
| Other Accession | NP_004719.2 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 87344 Da |
DDX21 Antibody (N-term) - Additional info | |
| Gene ID 9188 | |
| Other Names DDX21; Nucleolar RNA helicase 2; DEAD box protein 21; Gu-alpha; Nucleolar RNA helicase Gu; Nucleolar RNA helicase II; RH II/Gu | |
| Target/Specificity This DDX21 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-156 amino acids from the N-terminal region of human DDX21. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions DDX21 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
DDX21 Antibody (N-term) - Protein Information | |
| Name DDX21 | |
| Function Can unwind double-stranded RNA (helicase) and can fold or introduce a secondary structure to a single-stranded RNA (foldase). Functions as cofactor for JUN-activated transcription Involved in rRNA processing | |
| Cellular Location Nucleus, nucleolus. | |
DDX21 Antibody (N-term) - Related products
DDX21 Antibody (N-term) - Application data
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DDX21 Antibody (N-term) (Cat. #AP17238a) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the DDX21 antibody detected the DDX21 protein (arrow).
DDX21 Antibody (N-term) - Research Areas
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BACKGROUND
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription.
REFERENCES
Holmstrom, T.H., et al. J. Biol. Chem. 283(11):7046-7053(2008) Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007) Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) : Olsen, J.V., et al. Cell 127(3):635-648(2006) Nousiainen, M., et al. Proc. Natl. Acad. Sci. U.S.A. 103(14):5391-5396(2006)
