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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PITPNM1 Antibody (N-term)   

PITPNM1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PITPNM1 Antibody (N-term) AP17243a
    PITPNM1 Antibody (N-term) (Cat. #AP17243a) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the PITPNM1 antibody detected the PITPNM1 protein (arrow).
  • WB - PITPNM1 Antibody (N-term) AP17243a
    PITPNM1 Antibody (N-term) (Cat. #AP17243a) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the PITPNM1 antibody detected the PITPNM1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O00562
Other Accession NP_004901.2, NP_001124320.1
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 134848 Da
Antigen Region 143-171 aa
Additional Information
Gene ID 9600
Other Names Membrane-associated phosphatidylinositol transfer protein 1, Drosophila retinal degeneration B homolog, Phosphatidylinositol transfer protein, membrane-associated 1, PITPnm 1, Pyk2 N-terminal domain-interacting receptor 2, NIR-2, PITPNM1, DRES9, NIR2, PITPNM
Target/Specificity This PITPNM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-171 amino acids from the N-terminal region of human PITPNM1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPITPNM1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms DRES9, NIR2, PITPNM
Function Regulates RHOA activity, and plays a role in cytoskeleton remodeling. Necessary for normal completion of cytokinesis. Plays a role in maintaining normal diacylglycerol levels in the Golgi apparatus. Binds phosphatidyl inositol phosphates (in vitro). May catalyze the transfer of phosphatidylinositol and phosphatidylcholine between membranes (By similarity). Necessary for maintaining the normal structure of the endoplasmic reticulum and the Golgi apparatus. Required for protein export from the endoplasmic reticulum and the Golgi. Binds calcium ions.
Cellular Location Cytoplasm. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Endoplasmic reticulum membrane; Peripheral membrane protein. Lipid droplet. Cleavage furrow. Midbody. Note=Peripheral membrane protein associated with Golgi stacks in interphase cells. A minor proportion is associated with the endoplasmic reticulum. Associated with lipid droplets Dissociates from the Golgi early on in mitosis and localizes to the cleavage furrow and midbody during cytokinesis
Tissue Location Ubiquitous..
Research Areas
Citations (0)

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PITPNM1 belongs to a family of membrane-associated phosphatidylinositol transfer domain-containing proteins that share homology with the Drosophila retinal degeneration B (rdgB) protein (Ocaka et al., 2005 [PubMed 15627748]).


Burgis, N.E., et al. J. Biol. Chem. 282(6):3531-3538(2007)
Olsen, J.V., et al. Cell 127(3):635-648(2006)
Litvak, V., et al. Nat. Cell Biol. 7(3):225-234(2005)
Amarilio, R., et al. J. Biol. Chem. 280(7):5934-5944(2005)
Ocaka, L., et al. Cytogenet. Genome Res. 108(4):293-302(2005)

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$ 295.00
$ 99.00
Cat# AP17243a
(40 western blots)
Availability: In Stock
Bulk Size
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